Dietary orotic acid affects antioxidant enzyme mRNA levels and oxidative damage to lipids and proteins in rat liver
✍ Scribed by Masashi Morifuji; Yoritaka Aoyama
- Book ID
- 108473961
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 73 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0955-2863
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## Abstract In the present work we investigated the in vitro effect of 3‐hydroxy‐3‐methylglutarate (HMG) that accumulates in 3‐hydroxy‐3‐methylglutaryl‐CoA lyase deficiency (HMGLD) on important parameters of oxidative stress in rat cerebral cortex. It was observed that HMG induced lipid peroxidatio