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Dietary Exposure Estimation of Benzo[a]pyrene and Cancer Risk Assessment

โœ Scribed by Lee, Byung Mu; Shim, Geun Ae

Book ID
126787565
Publisher
Taylor and Francis Group
Year
2007
Tongue
English
Weight
74 KB
Volume
70
Category
Article
ISSN
1087-2620

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3-hydroxy-benzo(a)pyrene (3-OH-B(a)P) and mutagenic activity in rat urine were determined after the oral administration of benzo(a)pyrene given in three repeated doses of 10, 20 and 50 pmol kg-'. The procedure for the determination of 3-OH-B(a)P consisted of enzymic hydrolysis, separation and HPLC-a