Dietary cholesterol, blood cholesterol and cardiovascular disease

✍ Scribed by John Stanley

• Publisher: Wiley (John Wiley & Sons)
• Year: 2010
• Tongue: English
• Weight: 142 KB
• Volume: 22
• Category: Article
• ISSN: 0956-666X
• DOI: 10.1002/lite.201000024

✦ Synopsis

Abstract

Cholesterol is an essential cellular nutrient and homeostatic mechanisms exist to balance rates of cholesterol production and utilisation and minimise effects of dietary cholesterol on blood cholesterol and hence cardiovascular disease risk. In non‐diabetic populations, there is little evidence from epidemiological studies for associations between dietary cholesterol or the consumption of cholesterol rich foods and cardiovascular disease risk, or from intervention trials for major effects of dietary cholesterol on blood cholesterol levels. By contrast, evidence is emerging from epidemiological studies that consumption of eggs is associated with cardiovascular disease in diabetics, and from intervention trials that dietary cholesterol has greater effects on blood cholesterol levels in insulin resistant people. Since insulin plays a role in cholesterol homeostasis, these are not surprising findings.