Dietary agents as histone deacetylase in
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Melinda C. Myzak; Emily Ho; Roderick H. Dashwood
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Article
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2006
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John Wiley and Sons
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English
β 109 KB
## Abstract In cancer cells, an imbalance often exists between histone acetyltransferase (HAT) and histone deacetylase (HDAC) activities, and various drug companies are actively seeking competitive HDAC inhibitors for chemotherapeutic intervention. Cancer cells appear to be more sensitive than nont