Regulation of bile acid synthesis. II. E
✍
Douglas M. Heuman; Z. Reno Vlahcevic; Marsha L. Bailey; Phillip B. Hylemon
📂
Article
📅
1988
🏛
John Wiley and Sons
🌐
English
⚖ 761 KB
Bile acid synthesis is believed to be regulated by bile salts returning to the liver via the portal vein and suppressing cholesterol 7a-hydroxylase, the rate-limiting enzyme in the bile acid biosynthesis pathway. In order to characterize the relative effectiveness of bile salts in regulating bile ac