Effects of treatment with deoxycholic acid and chenodeoxycholic acid on the hepatic synthesis of cholesterol and bile acids in healthy subjects
β Scribed by Curt Einarsson; Carl-Gustaf Hillebrant; Magnus Axelson
- Book ID
- 111721478
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 97 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0270-9139
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We determined the serum concentrations of cholic, chenodeoxycholic and deoxycholic acids in portal and peripheral venous blood in 9 gallstone-free patients and 39 patients with cholesterol gallstones during standardized cholecystectomy . An accurate and specific gas chromatographicmass spectrometric
Bile acid synthesis is believed to be regulated by bile salts returning to the liver via the portal vein and suppressing cholesterol 7a-hydroxylase, the rate-limiting enzyme in the bile acid biosynthesis pathway. In order to characterize the relative effectiveness of bile salts in regulating bile ac