Diels-Alder approach to bicyclic .alpha.-hydroxy ketones. Facile ketol rearrangements of strained .alpha.-hydroxy ketones
โ Scribed by Creary, Xavier; Inocencio, Pamela A.; Underiner, Ted L.; Kostromin, Ray
- Book ID
- 127107452
- Publisher
- American Chemical Society
- Year
- 1985
- Tongue
- English
- Weight
- 1019 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0022-3263
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๐ SIMILAR VOLUMES
A highly regio-and stereoselective Diels-Alder reaction between dienophiles of type I and dienes of type I1 (Scheme I ) gives rise to Diels-Alder adducts of type 111. Upon treatment with BF,. Et,O, these adducts are smoothly converted into the corresponding enones (Scheme 6). Under mild acidic condi
Transition Metal/Base-Catalyzed Aldol Reactions of Isocyanoacetic Acid Derivatives with Prochiral Ketones, a Straightforward Approach to Stereochemically Defined ฮฒ,ฮฒ-Disubstituted-ฮฒ-hydroxy-. alpha.amino Acids. Scope and Limitations. -Methyl isocyanoacetate (II) undergoes aldol type reactions with