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Diastereoselectivity and enantioselectivity in the addition of chiral imines of 2-methylcyclohexanone to crotonic and methacrylic acid esters

✍ Scribed by Ivan Jabin; Gilbert Revial; Alain Tomas; Pascale Lemoine; Michel Pfau


Book ID
103977209
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
1008 KB
Volume
6
Category
Article
ISSN
0957-4166

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High pressure activation in the asymmetr
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High pressure-mediated Michael addition of chiral imines derived from 2-methylcyclopentanone, 2-methylcyclohexanone and optically active 1-phenylethylamine, to methyl and phenyl crotonates was investigated. The corresponding adducts were obtained in fair yields and with a high degree of regio-, dias