Diastereoselective Zinco-Cyclopropanation of Chiral Allylic Alcohols with gem-Dizinc Carbenoids.
โ Scribed by Jean-Francois Fournier; Simon Mathieu; Andre B. Charette
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 29 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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โฆ Synopsis
Abstract
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๐ SIMILAR VOLUMES
The ene reaction of PTAD with the chiral allylic alcohol 4-methyl-3-penten-2-01 exhibits high threo diastereoselectivity in non polar solvents, whereas in polar solvents the diastereoselectivity decreases substas!ially. These results are discussed in terms of a steering effect between the hydroxyl a
Regio-and Diastereoselective Ene Reaction of 4-Phenyl-1,2,4triazoline-3,5-dione with Chiral Allylic Alcohols and Their Derivatives. -Allylic alcohols and their methyl ethers and acetates react with triazolinedione (II) with complete regioselectivity and, in most cases, with high diastereoselectivit