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Diastereoselective synthesis of unsaturated 1,4-amino alcohols as a biologically important moiety

โœ Scribed by Young Hoon Jung; Ji Duck Kim


Book ID
105672987
Publisher
Springer
Year
2005
Tongue
English
Weight
791 KB
Volume
28
Category
Article
ISSN
0253-6269

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Diastereoselective synthesis of 1,4-amin
โœ Stephen G. Pyne; Zemin Dong ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 206 KB

A diastereoselective synthesis of 1,4-amino alcohols can be achieved from a highly diastereoselective reduction of a y-keto-vinyl sulfoximine followed by C-methylation and then a highly diastereoselective palladium(0) catalysed ailylic sulfoximine to allylic sulfinamide rearrangement with 1,4-stereo