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Diastereoselective Synthesis of Seven- and Eight-Membered Oxabicycles via Prins-Type Cyclization.

โœ Scribed by Hyun Jung Kang; Sang Hee Kim; Ae Nim Pae; Hun Yeong Koh; Moon Ho Chang; Kyung Il Choi; So-Yeop Han; Yong Seo Cho


Book ID
101978340
Publisher
John Wiley and Sons
Year
2005
Weight
47 KB
Volume
36
Category
Article
ISSN
0931-7597

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The reaction of aldehyde with homoaUyl alcohols mediated by indium trichloride generated 4-chlorotetrahydropyrans in high yields and with high stereoselectivity. The same type of compounds can be generated through a single step, multi-component coupling between aldehyde and allyl bromide mediated by