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Diastereoselective synthesis of 4-hydroxycyclopentenones from (3-alkoxycarbonyl-2-oxo-propylidene)triphenylphosphorane and chiral glyoxals

✍ Scribed by Minoru Hatanaka; Yasuhiro Tanaka; Ikuo Ueda


Book ID
103408676
Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
169 KB
Volume
36
Category
Article
ISSN
0040-4039

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One pot diastereoselective synthesis of
✍ Amal Feddouli; Moulay Youssef Ait Itto; Aïssa Hasnaoui; Didier Villemin; Paul-Al 📂 Article 📅 2004 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 200 KB

## Abstract Herein we report an efficient one pot synthesis of new chiral 4,5‐dihydro‐4‐arylspiro[1,3,4‐thiadiazole]‐5,2′‐camphane‐2‐carboxylic acid ethyl esters **5–7** and 4,5‐dihydro‐3‐arylspiro[1,4,2‐oxathiazole]‐5,2′‐camphane **11–13**, using 1,3‐dipolar cycloaddition of nitrilimines 2–4 and n