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Diastereoselective synthesis of (2S,3R) 2-carboxy-3-pyrrolidine acetic acid, a simple kainic acid analogue

✍ Scribed by Nicole Lunglois; Ratremaniaina Z. Andriamialisoa


Publisher
Elsevier Science
Year
1991
Tongue
French
Weight
155 KB
Volume
32
Category
Article
ISSN
0040-4039

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Diastereoselective synthesis of (1S,2S,3
✍ Elena BuΓ±uel; Carlos Cativiela; Maria D. Diaz-de-Villegas πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 English βš– 430 KB

The tide compounds were prepared from key intermediates readily obtained by the stereoselective Diels-Alder reaction of (Z)-2-pbenyl-4-[(S)-2,2-dimethyl-l,3dioxolan-4-ylmethylene]-5(4H)-oxazolone, a chiral az-lactone derived from (R)glyceraldehyde and cyclopentadiene.