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Diastereoselective Synthesis of 2-Amino-4-phosphonobutanoic Acids by Conjugate Addition of Lithiated Schoellkopf′s Bislactim Ethers to Vinylphosphonates.

✍ Scribed by Maria Ruiz; M. Carmen Fernandez; Aniana Diaz; Jose M. Quintela; Vicente Ojea


Publisher
John Wiley and Sons
Year
2004
Weight
293 KB
Volume
35
Category
Article
ISSN
0931-7597

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Enantioselective Synthesis of α-Amino Ac
✍ Denis Lucet; Stéphane Sabelle; Olivier Kostelitz; Thierry Le Gall; Charles Miosk 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 376 KB 👁 1 views

The addition of the potassium salt of (R)-or (S)-4-phenyl-products were converted into α-amino acids and monosubstituted 1,2-diamines of high enantiomeric purity. 2-oxazolidinone to monosubstituted nitroalkenes proceeded with very good diastereoselectivity. Several of the addition derivatives are in