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Diastereoselective reduction of N-phthaloyl α-amino ketones: synthesis of syn-3-amino-1,2-diol derivatives

✍ Scribed by Saumitra Sengupta; Debarati Sen Sarma

Book ID
104211537
Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
75 KB
Volume
42
Category
Article
ISSN
0040-4039

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✦ Synopsis

LiAlH(OBu-t)

3 reduction of the chiral-pool derived N-phthaloyl a-amino-a%-acetoxy ketones has led to a facile diastereoselective synthesis of syn-3-amino-1,2-diols ( > 75% de).

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ChemInform Abstract: Stereoselective Red
ChemInform Abstract: Stereoselective Reduction of N-Phthaloyl α-Amino Ketones: An Expeditious Synthesis of Statine.
✍ Saumitra Sengupta; Debarati Sen Sarma 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 1 views

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