Diastereoselective Henry Reaction Catalyzed by Guanidine—Thiourea Bifunctional Organocatalyst.
✍ Scribed by Yoshihiro Sohtome; Nobuko Takemura; Toshitsugu Iguchi; Yuichi Hashimoto; Kazuo Nagasawa
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 27 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Novel bifunctional catalysts having guanidine and thiourea functional groups were developed for the asymmetric Henry (nitroaldol) reaction. Various structural developments of the catalyst revealed that the compound having an octadecyl‐substituted guanidine and thiourea groups linked wit
## Abstract magnified image A highly enantioselective aza‐Henry reaction of imines with nitromethane was achieved with a reactive guanidine‐thiourea bifunctional organocatalyst affording β‐nitroamines with high enantioselectivity (up to 96% __ee__). The diastereo‐ and enantioselective version of t
## Abstract For Abstract see ChemInform Abstract in Full Text.