Diastereoselective and enantioselective catalysis of the carbonyl-ene reaction with fluoral

✍ Scribed by Koichi Mikami; Tomoko Yajima; Masahiro Terada; Etsuko Kato; Masamichi Maruta

• Publisher: Elsevier Science
• Year: 1994
• Tongue: English
• Weight: 327 KB
• Volume: 5
• Category: Article
• ISSN: 0957-4166
• DOI: 10.1016/0957-4166(94)80058-8

✦ Synopsis

The chid titanium complex-catalyzed carbonyl-ene reaction with fluoral is shown to serve as an efficient route for the syu-diastereoselective and enantioselective synthesis of CF3substituted compounds of biological and synthetic importance. ~g~~~ne compounds are com~nly employed in aiming and biological chemistry, Recently,