𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Diastereoselective addition of Di-(trimethylsilyl)phosphite to chiral N-(R)-α-methylbenzyl and N-(1-methoxycarbonyl-iso-pentyl) Schiff bases of various aldehydes

✍ Scribed by Jarosław Lewkowski; Rafał Karpowicz

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
185 KB
Volume
21
Category
Article
ISSN
1042-7163

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The addition of bis‐(trimethylsilyl) phosphite to chiral imines of several aldehydes was diastereoselective. The separation of predominant diastereoisomers of a majority of formed aminophosphonic acids has been observed. Moreover, the ferrocene‐derived acid 5d occurred in diastereoselectivity up to 100%. © 2010 Wiley Periodicals, Inc. Heteroatom Chem 21:326–331, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20624

📜 SIMILAR VOLUMES

Diastereoselective addition of hypophosp
Diastereoselective addition of hypophosphorous acid to N-(R)-α-methylbenzyl-substituted schiff bases
✍ Jarosław Lewkowski; Rafał Karpowicz; Małgorzata Rybarczyk 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 102 KB

## Abstract The addition of hypophosphorous acid to an azomethine bond of __N__‐(__R__)‐α‐methylbenzyl Schiff bases of a variety of aldehydes led to the formation of __N__‐(__R__)‐α‐methylbenzylamino‐(__S__)‐methanephosphonous acids in 100% diastereoselectivity. This fact allows us to suggest the p