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✦ LIBER ✦
Diastereocontrolled addition of organometallic reagents to S-chiral N-(tert-butanesulfinyl)-α-fluoroenimines
✍ Scribed by Camille Pierry; Ludivine Zoute; Philippe Jubault; Emmanuel Pfund; Thierry Lequeux; Dominique Cahard; Samuel Couve-Bonnaire; Xavier Pannecoucke
- Book ID
- 108285289
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- French
- Weight
- 159 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0040-4039
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Organometallic addition to tert-butanesufinyl ketimines derived from diaryl and aryl-heteroaryl ketones provided the corresponding a,a-diaryl and a-aryl-a-heteroaryl alkylamines in good yield with high diastereoselectivity. In many cases, imine facial selectivity is reversed on changing the organome