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Diaphanous-Related Formins Bridge Rho GTPase and Src Tyrosine Kinase Signaling

✍ Scribed by Tomoko Tominaga; Erik Sahai; Pierre Chardin; Frank McCormick; Sara A. Courtneidge; Arthur S. Alberts

Book ID: 117736366
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 516 KB
Volume: 5
Category: Article
ISSN: 1097-2765
DOI: 10.1016/s1097-2765(00)80399-8

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✦ Synopsis

at San Francisco anous-related formin (DRF) homologous to p140 mDia1 (Watanabe et al., 1997), which we call mDia2 (Alberts et Cancer Center San Francisco, California 94115 al., 1998a). The DRFs constitute a subfamily of formin homology (FH) proteins that are Rho-GTP dependent † Chester Beatty Labs Institute of Cancer Research London SW3 6JB effectors (Wasserman, 1998). The DRFs are conserved in budding yeast (Bni1, Bnr1), invertebrates (Diaphanous), United Kingdom ‡ Institut de Pharmacologie du CNRS 06560 and mammals (mDia1/DFNA1, DIA, mDia2) (Alberts et al.

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