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Dially disulfide from garlic induces apoptosis through caspase-dependent pathway in human breast cancer cell line, MCF-7

✍ Scribed by H.-L. Park; J.-H. Yang

Book ID: 117575750
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 122 KB
Volume: 59
Category: Article
ISSN: 0753-3322
DOI: 10.1016/s0753-3322(05)80090-3

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## Abstract Rotenone is an inhibitor of the mitochondrial electron transport chain complex I, resulting in the generation of reactive oxygen species (ROS). Rotenone has been shown to display anticancer activity through the induction of apoptosis in various cancer cells. However, the underlying mech