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Dialkylmethyl β-glycosides ofN-acetylmuramyl-L-alanyl-D-isoglutamine: Synthesis and protective antiinfection and cytotoxic activities

✍ Scribed by A. E. Zemlyakov; V. N. Tsikalova; V. V. Tsikalov; V. Ya. Chirva; E. L. Mulik; F. N. Kuzovlev; O. V. Kalyuzhin; M. V. Kiselevsky


Book ID
111456851
Publisher
SP MAIK Nauka/Interperiodica
Year
2008
Tongue
English
Weight
324 KB
Volume
34
Category
Article
ISSN
1068-1620

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## Abstract The syntheses of the acyclic MDP analogs 27–37 is described, the carbohydrate moiety of muramic acid being replaced by acyclic amino alcohol structures. Their preparation was accomplished by hydrolytic cleavage of the cyclic, disubstituted 3‐morpholinones 2–5 and protection of the free