Dialkyl 2H-1-Benzothiopyran-2,3-dicarboxylates via Intramolecular Wittig Reaction.
✍ Scribed by Rahim Hekmatshoar; Shahrzad Javanshir; Majid M. Heravi
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 16 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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## Abstract The title compounds 12, which are key intermediates for antitumoral diazaquinomycin A analogues, are obtained by intramolecular Wittig reaction of 1‐[3′,6′‐dimethoxy‐2′‐(α‐oxoacylamino)phenyl]alkyltriphenylphosphonium salts 11, which are prepared via lithiation of 2′,5′‐dimethoxy‐__N__‐
## Abstract The synthesis of 1‐bicyclo[3.2.2]nonene **(2)** and of 1 (7)‐bicyclo [3.2.2]nonene **(3)**, two isomeric bridged (__E__)‐cycloheptenes, by intramolecular __Wittig__ reaction is described. These ‘__Bredt__ olefins’ could not be isolated, but dimerized rapidly. In both cases, the main pro