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Diagnosis and quantitative detection of HSV DNA in samples from patients with suspected herpes simplex encephalitis

✍ Scribed by Ziyaeyan, Mazyar; Alborzi, Abdolvahab; Haghighi, Afshin Borhani; Jamalidoust, Marziyeh; Moeini, Mahsa; Pourabbas, Bahman

Book ID
121783971
Publisher
SciELO
Year
2011
Tongue
English
Weight
706 KB
Volume
15
Category
Article
ISSN
1413-8670

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In a two-centre study, the routine DNA preparation and PCR amplification protocols were compared for herpes simplex virus (HSV) detection in cerebrospinal fluids (CSFs) of 43 patients with suspected herpes simplex encephalitis (HSE). The combined clinical, radiological and laboratory results indicat

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## Abstract Herpes simplex virus (HSV) DNA in the cerebrospinal fluid (CSF) of children with herpes simplex encephalitis (HSE) was quantified and typed using the polymerase chain reaction (PCR) assay. During the acute phase, HSV‐DNA was detected in the CSF of 13 patients with HSE, including 5 neona