Hepatitis B core antigen was measured in sera of patients with acute and chronic hepatitis B virus infection by a modified radioimmunoassay based on high molarity treatment of samples to avoid masking of antigen by homologous antibody. A good correlation between hepatitis B core antigen levels and s
Diagnosis and prophylaxis in acute hepatitis B exposure
β Scribed by Lars Magnius
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- English
- Weight
- 219 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0146-6615
No coin nor oath required. For personal study only.
β¦ Synopsis
This symposium is intended to be on rapid laboratory methods of diagnosis with special reference to hepatitis B. In fact the most urgent situations seem to be those involving presumed exposure to hepatitis B and whether or not specific gammaglobulin should be given. I am also going to discuss to what extent it is advisable to test for infectivity markers, such as DNA polymerase, e-antigen, etc in this situation. What is needed is rapid decisions, and the need for rapid laboratory tests is dependent on the extent they are needed to support these decisions.
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In the present study we have investigated 53 patients with a spectrum of acute and chronic hepatitis B virus (HBV) infection for the presence of leucocyte HBV-DNA with the aid of molecular techniques. HBV-DNA was detected in peripheral blood mononuclear cells of 31 of 45 (69%) of chronic HBsAg carri
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