Diagnosis and management of Crigler-Najjar syndrome
β Scribed by P. L. M. Jansen
- Book ID
- 120907826
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 141 KB
- Volume
- 158
- Category
- Article
- ISSN
- 0340-6997
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π SIMILAR VOLUMES
Crigler-Najjar (CN) syndrome is a congenital familial nonhemolytic jaundice associated with high level of unconjugated bilirubin due to deficient uridine diphosphate glucuronosyltransferase (UDPG-T) activity in the liver. The aim of this report is to emphasize the need for increased awareness of thi
The liver may be involved in metabolic disorders in two ways. (i) Due to its critical role in several metabolic pathways, the liver may be the major site of expression of a biochemical abnormality, For example, in Type I Crigler-Najjar syndrome, absence of hepatic bilirubin glucuronyl transferase ac