Crigler-Najjar (CN) syndrome is a congenital familial nonhemolytic jaundice associated with high level of unconjugated bilirubin due to deficient uridine diphosphate glucuronosyltransferase (UDPG-T) activity in the liver. The aim of this report is to emphasize the need for increased awareness of thi
Pregnancy in Crigler-Najjar syndrome. Case report
β Scribed by W. G. TAYLOR; S. A. WALKINSHAW; R. G. FARQUHARSON; R. A. FISKEN; I. T. GILMORE
- Book ID
- 111155363
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 151 KB
- Volume
- 98
- Category
- Article
- ISSN
- 1470-0328
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## which reliable administration of phototherapy cannot This study represents a multicenter survey on the be guaranteed. (HEPATOLOGY 1996;24:311-315.) management of patients with Crigler-Najjar syndrome (CNS) type 1. The aim of the survey was to find guiding principles for physicians in the care o
Crigler-Najjar syndrome type I (CN-I) is an autosomal recessive condition characterized by severe unconjugated hyperbilirubinemia caused by the lack of bilirubin-UDP-glucuronosyltransferase (B-UGT) activity in the liver. Two B-UGTs are coded for by a gene complex (UGT1) that maps to chromosome 2q37