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Diabetogenic Action of Alloxan Derivatives

✍ Scribed by BRÜCKMANN, G.; WERTHEIMER, E.


Book ID
109545519
Publisher
Nature Publishing Group
Year
1945
Tongue
English
Weight
247 KB
Volume
155
Category
Article
ISSN
0028-0836

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Diabetogenic action of alloxan-like comp
✍ S. P. C. Tait; M. Poje; B. Rocic; S. J. H. Ashcroft 📂 Article 📅 1983 🏛 Springer 🌐 English ⚖ 485 KB

Dehydrouramil hydrate hydrochloride (DHU) is an analogue of alloxan which retains the in vivo diabetogenic activity of alloxan but, in contrast to alloxan, is stable in aqueous media at physiological pH. Using rat islets of Langerhans, we have studied the acute effects of DHU on B cell function. Glu