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Effect of adaptation to cold on sensitivity of animals to the diabetogenic action of alloxan

✍ Scribed by Yu. P. Shorin; V. G. Selyatitskaya; G. I. Nepomnyashchikh; N. A. Pal'chikova; R. R. Khodova

Publisher
Springer US
Year
1984
Tongue
English
Weight
249 KB
Volume
98
Category
Article
ISSN
0007-4888

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Diabetogenic action of alloxan-like comp
Diabetogenic action of alloxan-like compounds: The effect of dehydrouramil hydrate hydrochloride on isolated islets of langerhans of the rat
✍ S. P. C. Tait; M. Poje; B. Rocic; S. J. H. Ashcroft πŸ“‚ Article πŸ“… 1983 πŸ› Springer 🌐 English βš– 485 KB

Dehydrouramil hydrate hydrochloride (DHU) is an analogue of alloxan which retains the in vivo diabetogenic activity of alloxan but, in contrast to alloxan, is stable in aqueous media at physiological pH. Using rat islets of Langerhans, we have studied the acute effects of DHU on B cell function. Glu