## Highly electrophilic phosphorylating species, generated from an appropriately protected 5 '-U-(1 -H-phasphonate) nucleoside block 4 or 5 and pivaloyl chloride, followed by an oxidation step, has been used for the first time to introduce the branching phosphate vicinal to an internucleotidyl2 '
β¦ LIBER β¦
Di- and Oligonucleotide Synthesis Using H-Phosphonate Chemistry
β Scribed by Jacek Stawinski; Roger Stroemberg
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 8 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Synthesis of βbranchedβ trinucleotide us
β
A. FΓΆldesi; N. Balgobin; J. Chattopadhyaya
π
Article
π
1989
π
Elsevier Science
π
French
β 276 KB
Solution-Phase Synthesis of Phosphorothi
β
Ilaria Adamo; CΓ©cile Dueymes; Andreas SchΓΆnberger; Aude-Emmanuelle Navarro; Albe
π
Article
π
2006
π
John Wiley and Sons
π
English
β 285 KB
Large-scale oligonucleotide synthesis by
β
Barbara L. Gaffney; Roger A. Jones
π
Article
π
1988
π
Elsevier Science
π
French
β 388 KB
H-phosphonate oligonucleotide synthesis
β
Hetian Gao; Barbara L. Gaffney; Roger A. Jones
π
Article
π
1991
π
Elsevier Science
π
French
β 303 KB
Thioctic acid modification of oligonucle
β
Jennifer A. Dougan; Andrew. K. Reid; Duncan Graham
π
Article
π
2010
π
Elsevier Science
π
French
β 301 KB
The H-phosphonate of a derivative of thioctic acid (TA) was synthesised and used to introduce a disulfide moiety at the 5 0 -end of oligonucleotides. This method overcomes the difficulties experienced with the phosphoramidite approach when employing a cyclic disulfide in the starting alcohol. The di
First synthesis of H-phosphonate oligonu
β
Takeshi Wada; Fumio Honda; Yuichi Sato; Mitsuo Sekine
π
Article
π
1999
π
Elsevier Science
π
French
β 284 KB