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Dextranation of Bioreducible Cationic Polyamide for Systemic Gene Delivery

โœ Scribed by Lin, Chao ;Song, Yanyan ;Lou, Bo ;Zhao, Peng

Book ID
125527500
Publisher
IOS Press
Year
2014
Tongue
English
Weight
813 KB
Volume
24
Category
Article
ISSN
0959-2989

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Synthesis of bifunctional cationic compo
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โœ Tan Ren; Guisheng Zhang; Dexi Liu ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 97 KB

Bifunctional cationic compound carrying trivalent galactosides as the cell targeting ligand and DAB-dendr-(NH 2 ) 8 (generation 2.0) as the DNA binding domain was synthesized for gene delivery to hepatocytes. DAB-dendr-(NH 2 ) 4 (generation 1.0) conjugated with a hydrocarbon chain was used as a scaf