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Dextran-protamine polycation: An efficient nonviral and haemocompatible gene delivery system

โœ Scribed by Jane Joy Thomas; M.R. Rekha; Chandra P. Sharma


Book ID
108100027
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
760 KB
Volume
81
Category
Article
ISSN
0927-7765

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Background Nonviral ex vivo local gene therapy systems consisting of regulated gene expression vectors and cellular delivery platforms represent a novel strategy for tissue repair and regeneration. We introduced a hypoxiaregulated plasmid-based system into mouse neural stem cells (NSCs) as an effici