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Dexmedetomidine-induced cerebral hypoperfusion exacerbates ischemic brain injury in rats

✍ Scribed by Takaaki Nakano; Hirotsugu Okamoto

Book ID
106183299
Publisher
Springer
Year
2009
Tongue
English
Weight
557 KB
Volume
23
Category
Article
ISSN
0913-8668

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## Abstract The proinflammatory cytokine interleukin‐1 (IL‐1) is a key mediator of inflammation in cerebral ischemia, but its precise mechanisms of action remain elusive. Temperature is critical to outcome in brain injury and given the importance of IL‐1 in pyrogenesis this has clear mechanistic im