Lentivirus-mediated RNA interference rev
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Xueshi Ye; Ting Liu; Yuping Gong; Bohui Zheng; Wentong Meng; Yamei Leng
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Article
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2009
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Elsevier Science
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English
⚖ 464 KB
Multidrug-resistance (MDR) is a major hindrance to successful chemotherapy. The emergence of MDR is multi-factorial. Among them, the MDR1 gene/P-glycoprotein (P-gp) is a popular and important reason. In our study, an MDR1 single-factorial drug-resistant leukemia cell line K562/MDR1 was constructed v