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Dexamethasone regulates glutamine synthetase expression in rat lung

✍ Scribed by Peter Sarantos; David Howard; Wiley W. Souba


Book ID
116030917
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
816 KB
Volume
42
Category
Article
ISSN
1532-8600

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Metabolite control of glutamine synthetase expression (by glutamine) was studied in L6 skeletal muscle cells. Depletion of glutamine from the culture medium for 24 hours resulted in a 3-4-fold increase in glutamine synthetase activity. This effect was blocked by cycloheximide but not by actinomycin