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Developmental toxicity study for preventive and therapeutic vaccines in the rabbit

✍ Scribed by Linda Allais; Mariline Leroy; Jean-Yves Guyot


Book ID
113875537
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
258 KB
Volume
28
Category
Article
ISSN
0890-6238

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Developmental toxicity studies of caprol
✍ Dr. Shayne C. Gad; Keith Robinson; David G. Serota; Barbara R. Colpean πŸ“‚ Article πŸ“… 1987 πŸ› John Wiley and Sons 🌐 English βš– 888 KB

Caprolactam was evaluated for developmental toxicity potential in both rats and rabbits by the oral route. In rats dosed on days 6-15 of gestation with 100,500 or 1000 mg/kg/day of caprolactam, the maternal survival rate was significantly lower in the high-dose group and implantation efficiencies we