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Developmental Toxicity Studies in Mice, Rats, and Rabbits with the Anticonvulsant Gabapentin

✍ Scribed by Judith A. Petrere; John A. Anderson

Book ID
115608391
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
269 KB
Volume
23
Category
Article
ISSN
0272-0590

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Developmental toxicity studies of caprol
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✍ Dr. Shayne C. Gad; Keith Robinson; David G. Serota; Barbara R. Colpean πŸ“‚ Article πŸ“… 1987 πŸ› John Wiley and Sons 🌐 English βš– 888 KB

Caprolactam was evaluated for developmental toxicity potential in both rats and rabbits by the oral route. In rats dosed on days 6-15 of gestation with 100,500 or 1000 mg/kg/day of caprolactam, the maternal survival rate was significantly lower in the high-dose group and implantation efficiencies we