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Developmental toxicity of 2-butin-1,4-diol following oral administration to the rat

✍ Scribed by Jürgen Hellwig; Maren Beth; Hans-Joachim Klimisch


Book ID
119539294
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
786 KB
Volume
92
Category
Article
ISSN
0378-4274

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Subacute oral toxicity of 2-butyne-1,4-d
✍ Ryszard A. Jedrychowski; Teresa Czajkowska; Roman Gorny; Jan Stetkiewicz; Irena 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 465 KB

2-Butyne-1,4-diol was given to male and female Wistar 1mp:DAK rats by oral gavage for 28 consecutive days in daily doses of 1, 10 or 50 mg kg-' day-'. After 28 days all animals were necropsied. Blood samples were obtained and selected organs were weighed and prepared for histological examination. Tr