Developmental thyroid hormone insufficiency reduces expression of brain-derived neurotrophic factor (BDNF) in adults but not in neonates
β Scribed by S.M. Lasley; M.E. Gilbert
- Book ID
- 113825778
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 573 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0892-0362
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Levels of brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT3) mRNA expression were measured in a rodent model of traumatic brain injury (TBI) following unilateral injury to the cerebral cortex. To obtain reliable data on the co-expression of neurotrophin genes, adjacent coronal section
The administration of neurotrophins affects neuronal survival and growth, but less is known about their ability to modify the expression of growth associated genes following injury to CNS neurons. Here we characterize the effect of brain-derived neurotrophic factor (BDNF) on mRNA levels for Ta1 a-tu