Mammalian flavin-containing monooxygenase functions in the oxygenation of numerous xenobiotics containing a soft nucleophile, usually a nitrogen or sulfur. A total of five distinct flavin monooxygenase (FMO) isoforms are expressed in mammals. Individual isoforms are expressed in a sex-, age-, and ti
β¦ LIBER β¦
Developmental regulation of flavin-containing monooxygenase form 1 in the liver and kidney of fetal and neonatal rabbits
β Scribed by Shelley A. Larsen-Su; Sharon K. Krueger; Mei-Fei Yueh; Clifford B. Pereira; David E. Williams
- Book ID
- 113992997
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 122 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0006-2952
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## Abstract Three functional mouse flavinβcontaining monooxygenases (mFMOs) (i.e., mFMO1, mFMO3, and mFMO5) have been reported to be the major FMOs present in mouse liver. To examine the biochemical features of these enzymes, recombinant enzymes were expressed as maltoseβbinding protein fusion prot