Transferrin, the iron mobilization protein, and its mRNA are normally present in oligodendrocytes. Previous reports using myelin mutants have shown both a decrease in transferrin protein and mRNA when the oligodendrocyte population is compromised. In this study the shiverer mouse mutant in which the
Developmental dissociation of myelin synthesis and “myelin-associated” enzyme activities in the shiverer mouse
✍ Scribed by T. D. Bird; D. F. Farrell; S. Stranahan; E. Austin
- Publisher
- Springer
- Year
- 1980
- Tongue
- English
- Weight
- 568 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0364-3190
No coin nor oath required. For personal study only.
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Brain fractions of adult control (+/+) and shiverer (Shi/Shi) mice were investigated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and immunoblotting . Immunostaining with specific antisera against rat brain myelin-associated glycoprotein (MAG) was detected at about the 96-
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