Developmental changes in the expression of nicotinic acetylcholine receptor α-subunits in the rat heart
✍ Scribed by Magdalena Dvorakova; Katrin S. Lips; Dörthe Brüggmann; Jana Slavikova; Jitka Kuncova; Wolfgang Kummer
- Book ID
- 106138811
- Publisher
- Springer-Verlag
- Year
- 2004
- Tongue
- English
- Weight
- 714 KB
- Volume
- 319
- Category
- Article
- ISSN
- 0302-766X
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Neuronal nicotinic acetylcholine receptors (nAChRs) were expressed in J(enopus laevis oocytes after nuclear injection of complementary deoxyribonucleic acid (eDNA) expression vectors. The two receptor subtypes e4/nc~l and e3/nel were readily distinguishable from one another by ACh sensitivity and de
Standard two-electrode voltage-clamp techniques were used to investigate some of the pharmacological and functional properties of two types of rat neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes after pairwise injection of e3/74 or c~3/72 mRNAs. Currents of several gA amplitu