Subunit Composition of Nicotinic Acetylcholine Receptors in Neurons of the Rat Intracardiac Ganglia
β Scribed by H. E. Purnyn; M. V. Skok; O. V. Rikhalsky; V. I. Skok
- Book ID
- 110398697
- Publisher
- Springer US
- Year
- 2002
- Tongue
- English
- Weight
- 81 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0090-2977
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Standard two-electrode voltage-clamp techniques were used to investigate some of the pharmacological and functional properties of two types of rat neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes after pairwise injection of e3/74 or c~3/72 mRNAs. Currents of several gA amplitu
## Abstract Nicotinic acetylcholine receptors (nAChR) are widely distributed in the central nervous system, where they exert a modulatory influence on synaptic transmission. For the striatum, pharmacological evidence supports the presence of presynaptic Ξ±3Ξ²2\* and Ξ±4Ξ²2\* nAChR that modulate dopamin