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Developmental and tissue-specific differential regulation of the mouse dioxin-inducible P1-450 and P3-450 genes

✍ Scribed by Narendra Tuteja; Frank J. Gonzalez; Daniel W. Nebert


Book ID
118319562
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
851 KB
Volume
112
Category
Article
ISSN
0012-1606

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The environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) dioxin, produces a diverse set of biological responses which, in some cases, reflects the altered expression of specific genes. An intracellular receptor protein binds TCDD saturably and with high affinity and mediates several