𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Development of technology for purification of plasmid DNAs for pharmaceutical purposes

✍ Scribed by E. A. Volosnikova; N. I. Akulova; Ya. S. Gogina; G. M. Levagina; V. K. Mikhailova; L. R. Lebedev; V. F. Podgornyi; Yu. V. Telegina

Book ID
110152207
Publisher
SP MAIK Nauka/Interperiodica
Year
2010
Tongue
English
Weight
671 KB
Volume
46
Category
Article
ISSN
0003-6838

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Industrial Scale cGMP Purification of Ph
Industrial Scale cGMP Purification of Pharmaceutical Grade Plasmid-DNA
✍ J. Urthaler; W. Buchinger; R. Necina πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 339 KB

## Abstract The advances in gene therapy and genetic vaccination based on plasmid DNA result in an increasing demand of pharmaceutical grade plasmids produced under cGMP. A generic process consisting of a cell disintegration step followed by three different chromatography steps has been developed.

Identifying stabilizers of plasmid DNA f
Identifying stabilizers of plasmid DNA for pharmaceutical use
✍ Yuhong Zeng; Joshua D. Ramsey; Robert King; Michael Leviten; Ruth Mcguire; David πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 452 KB

To better address the need for developing stable formulations of plasmid DNA-based biopharmaceuticals, 37 compounds from a generally regarded as safe library were examined for their potential use as stabilizers. A plasmid DNA-based therapeutic vaccine, BHT-DNA, was used as a model system. Initial st