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Development of propranolol metabolism in the isolated perfused neonatal sheep liver

✍ Scribed by Gow, P.J.; Ghabrial, H.; Ching, M.S.; Shulkes, A.; Treepongkaruna, S.; Smallwood, R.A.; Morgan, D.J.


Book ID
122713790
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
341 KB
Volume
114
Category
Article
ISSN
0016-5085

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Neonatal hepatic propranolol elimination
✍ Paul J. Gow; Saard Treepongkaruna; Hany Ghabrial; Arthur Shulkes; Richard A. Sma πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 209 KB πŸ‘ 2 views

Using the isolated perfused neonatal sheep liver model, we examined the disposition of propranolol (n ‫ב‬ 8, age 0.25-10 days) and compared our findings with our previous study from the perfused near-term fetal sheep liver (Ring JA, et al. 1995. Drug Metab Dispos 23:190-196). Within 45 min of dosage