Neonatal hepatic propranolol elimination
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Paul J. Gow; Saard Treepongkaruna; Hany Ghabrial; Arthur Shulkes; Richard A. Sma
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Article
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2000
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John Wiley and Sons
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English
β 209 KB
π 2 views
Using the isolated perfused neonatal sheep liver model, we examined the disposition of propranolol (n β«Χ‘β¬ 8, age 0.25-10 days) and compared our findings with our previous study from the perfused near-term fetal sheep liver (Ring JA, et al. 1995. Drug Metab Dispos 23:190-196). Within 45 min of dosage