Conjugation of para-nitrophenol by the isolated perfused neonatal sheep liver

Neonatal hepatic propranolol elimination

Neonatal hepatic propranolol elimination: Studies in the isolated perfused neonatal sheep liver

✍ Paul J. Gow; Saard Treepongkaruna; Hany Ghabrial; Arthur Shulkes; Richard A. Sma 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 209 KB 👁 1 views

Using the isolated perfused neonatal sheep liver model, we examined the disposition of propranolol (n ‫ס‬ 8, age 0.25-10 days) and compared our findings with our previous study from the perfused near-term fetal sheep liver (Ring JA, et al. 1995. Drug Metab Dispos 23:190-196). Within 45 min of dosage