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Development of Potential Antitumor Agents. Synthesis and Biological Evaluation of a New Set of Sulfonamide Derivatives as Histone Deacetylase Inhibitors

✍ Scribed by Bouchain, Giliane; Leit, Silvana; Frechette, Sylvie; Khalil, Elie Abou; Lavoie, Rico; Moradei, Oscar; Woo, Soon Hyung; Fournel, Marielle; Yan, Pu T.; Kalita, Ann; Trachy-Bourget, Marie-Claude; Beaulieu, Carole; Li, Zuomei; Robert, Marie-France; MacLeod, A. Robert; Besterman, Jeffrey M.; Delorme, Daniel


Book ID
124158348
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
239 KB
Volume
46
Category
Article
ISSN
0022-2623

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✍ Chuanfei Jin; Yong-Ju Liang; Hongwu He; Liwu Fu πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 110 KB πŸ‘ 2 views

## Abstract A series of novel (thio)ureas containing the pyrimidinyl group was designed and synthesized. Their __in‐vitro__ antitumor activity against different human tumor cells was examined. Some of the compounds showed potential antitumor activity, which provided some hints for further studies o