Development of Potential Antitumor Agents. Synthesis and Biological Evaluation of a New Set of Sulfonamide Derivatives as Histone Deacetylase Inhibitors
β Scribed by Bouchain, Giliane; Leit, Silvana; Frechette, Sylvie; Khalil, Elie Abou; Lavoie, Rico; Moradei, Oscar; Woo, Soon Hyung; Fournel, Marielle; Yan, Pu T.; Kalita, Ann; Trachy-Bourget, Marie-Claude; Beaulieu, Carole; Li, Zuomei; Robert, Marie-France; MacLeod, A. Robert; Besterman, Jeffrey M.; Delorme, Daniel
- Book ID
- 124158348
- Publisher
- American Chemical Society
- Year
- 2003
- Tongue
- English
- Weight
- 239 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0022-2623
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## Abstract A series of novel (thio)ureas containing the pyrimidinyl group was designed and synthesized. Their __inβvitro__ antitumor activity against different human tumor cells was examined. Some of the compounds showed potential antitumor activity, which provided some hints for further studies o