✦ LIBER ✦

Development of Potent Inhibitors of Botulinum Neurotoxin Type B

✍ Scribed by Anne, Christine; Turcaud, Serge; Quancard, Jean; Teffo, Franck; Meudal, Hervé; Fournié-Zaluski, Marie-Claude; Roques, Bernard P.

Book ID: 125961448
Publisher: American Chemical Society
Year: 2003
Tongue: English
Weight: 152 KB
Volume: 46
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm0300680

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Thio-derived disulfides as potent inhibi

Thio-derived disulfides as potent inhibitors of botulinum neurotoxin type B: implications for zinc interaction

✍ Christine Anne; Armand Blommaert; Serge Turcaud; Anne-Sophie Martin; Hervé Meuda 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 198 KB

Design and synthesis of substrate-based

Design and synthesis of substrate-based inhibitors of botulinum neurotoxin type B metalloprotease

✍ Thorsten Oost; Chanokporn Sukonpan; Matthias Brewer; Michael Goodnough; William 📂 Article 📅 2003 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 363 KB

Synthesis of substrates and inhibitors o

Synthesis of substrates and inhibitors of botulinum neurotoxin type A metalloprotease*

✍ Sukonpan, C. ;Oost, T. ;Goodnough, M. ;Tepp, W. ;Johnson, E.A. ;Rich, D.H. 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 191 KB

Amino acid composition of Clostridium bo

Amino acid composition of Clostridium botulinum type B neurotoxin

✍ Bibhuti R. DasGupta; Mary A. Woody 📂 Article 📅 1984 🏛 Elsevier Science 🌐 English ⚖ 254 KB

Comparative sizes of type A and B botuli

Comparative sizes of type A and B botulinum neurotoxins

✍ Bibhuti R. DasGupta; H. Sugiyama 📂 Article 📅 1977 🏛 Elsevier Science 🌐 English ⚖ 367 KB

Partial Protection against Botulinum B N

Partial Protection against Botulinum B Neurotoxin-Induced Blocking of Exocytosis by a Potent Inhibitor of Its Metallopeptidase Activity

✍ Christine Anne; Serge Turcaud; Armand G. S. Blommaert; François Darchen; Eric A. 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 107 KB

## Abstract Clostridium botulinum __neurotoxins (BoNTs) cause botulism, which is characterized by a flaccid paralysis, through inhibition of acetylcholine release by peripheral cholinergic nerve terminals. This is due to the zinc metallopeptidase activity of the neurotoxin, cleaving one component (