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Development of physical dependence to lorazepam in rats: The effects of repeated short treatments, dose and age

✍ Scribed by Seher Korkmaz; Sten Carlsson; Göran Wahlström

Book ID
118599582
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
141 KB
Volume
8
Category
Article
ISSN
0924-977X

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Acute administration of lorazepam (0.25 and 0.5 mg/kg) and triazolam (0.075-0.25 mg/kg) significantly reduced the locomotor activity of rats placed in a holeboard for 10 min. Acute injections of lorazepam (0.25 and 0.5 mg/kg) and triazolam (0.05-0.25 mg/kg) also significantly reduced exploration, me